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UID:258@escience.washington.edu
DTSTART;TZID=America/Los_Angeles:20250313T163000
DTEND;TZID=America/Los_Angeles:20250313T172000
DTSTAMP:20250303T184021Z
URL:https://escience.washington.edu/events/uw-data-science-seminar-kris-bo
 uchard/
SUMMARY:UW Data Science Seminar: Kris Bouchard
DESCRIPTION:Please join us for a UW Data Science Seminar featuring Kris Bou
 chard\, an Assistant Adjunct Professor at UC Berkeley\, on Thursday\, Marc
 h 13th from 4:30 to 5:20 p.m. PT.\n\n\nThe seminar will be held in Hitchco
 ck Hall 132 – Campus Map.\n"Feedback control is a normative theory of n
 eural population dynamics"\n\nAbstract: Brain computations emerge from col
 lective dynamics of distinct neural populations. Behaviors including reach
 ing and speech are explained by principles of feedback control. However\, 
 if feedback control explains neural population dynamics is unknown. We cre
 ated dimensionality reduction methods that identify subspaces of neural po
 pulation data that are most feed-forward controllable (FFC) vs. feedback c
 ontrollable (FBC). We show that FBC and FFC subspaces diverge for dynamics
  generated by neuro-anatomical connectivity. In neural recordings from acr
 oss the brain\, we show that FBC subspaces were better decoders of externa
 l variables (e.g. reach velocity\, visual stimuli\, animal location). Comp
 ared to FFC subspaces\, FBC subspaces emerged from collective interactions
  of a population of neurons with distinct activity profiles. Finally\, in 
 M1/S1\, we revealed that FBC subspaces emphasize rotational dynamics due t
 o enhanced system stability\, while FFC subspaces emphasize scaling dynami
 cs. These results demonstrate feedback controllability is a novel\, normat
 ive theory of neural population dynamics\, and connect distinct neuronal p
 opulations to differing regimes of emergent dynamics carrying out distinct
  computations.\n\n  Biography:  Kris Bouchard is Assistant Adjunct Profess
 or in the Helen Wills Neuroscience Institute & Redwood Center for Theoreti
 cal Neuroscience at UC Berkeley. He is PI of the Neural Systems and Machin
 e Learning Lab (NSML) at UCB and Lead of the Computational Biosciences Gro
 up in the Scientific Data Division\, LBNL. The NSML lab is interdisciplina
 ry team that focuses on understanding how distributed neural circuits give
  rise to coordinated behaviors and perceptions. We take a multi-pronged ap
 proach to this problem by developing novel theoretical frameworks for neur
 al circuit function\, conducting in vivo neuroscience experiments\, and de
 veloping state of the art machine learning tools to address diverse system
 s biology questions. On the neuroscience side\, we investigate functional 
 organization and dynamic coordination in the brain by combining in vivo mu
 lti-scale electrophysiology and optogenetics in rodents. This multi-modal\
 , multi-scale approach provides the simultaneous breadth of coverage and s
 patio-temporal resolution required to determine neural computations at the
  speed of thought. On the computational side\, we aim to reveal the proces
 ses that generate complex (neuro-) biological data by combining ideas from
  control theory\, information theory\, high-dimensional statistical learni
 ng\, statistical mechanics\, and modern deep learning to develop novel met
 hods and apply them to general biological and neuroscience problems.\nThe 
 2024-2025 seminars will be held in person\, and are free and open to the p
 ublic.
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